We can collect various human organoids
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Enables new era of rapid, low-cost high throughput screening and identification
Alvus's organoids merge the benefits of cell lines and 3D organoids.
Cell Line
3D Organoid
Alvus Health
Physiology
Low
High
High
Throughput
High
Low
High
Cost efficiency
High
Low
High
Standarization
High
Low
High
Automation and Screening
Alvus's organoids easily integrate with high-throughput automation, facilitate cell transfection for gene editing, and streamline imaging data collection.
Automation and Screening
Alvus's organoids easily integrate with high-throughput automation, facilitate cell transfection for gene editing, and streamline imaging data collection.
Automation and Screening
Alvus's organoids easily integrate with high-throughput automation, facilitate cell transfection for gene editing, and streamline imaging data collection.
High-throughput automated organoid culturing and AI-enabled phenotypic analysis optimizes and amplifies intricate biological research
Collaborating with pioneering centers advancing lab automation, such as the Harvard ICCB-Longwood Screening Facility, Alvus harnesses high-throughput organoid screening to explore small molecules and functional genomics.
Healthy
Crypt-villus morphology via nuclear staining
CRC
Crypt-villus morphology via nuclear staining
Healthy
Permeability via ZO-1
Healthy
Stem cells via LGR5
Scalable Data:
All-round Phenotypic Profiling via Multiplex Staining and Sequencing
Phenotypic assays monitor the establishment of cell morphology and phenotype of interest in a target-agnostic manner, enabling the exploration of vast biological space. By leveraging advanced multiplex imaging techniques, we can profile the molecular characteristics of organoids at the single-cell level.
CRC
Permeability via ZO-1
Healthy
Goblet cells via MUC-2
CRC
Enterocytes via ALPI
Healthy
Enterocytes via ALPI
CRC
Goblet cells via MUC-2
CRC
Stem cells via LGR5
Healthy
Crypt-villus morphology via nuclear staining
CRC
Crypt-villus morphology via nuclear staining
Healthy
Permeability via ZO-1 staining
CRC
Permeability via ZO-1 staining
Healthy
Stem cells via LGR5 staining
CRC
Crypt-villus morphology via nuclear staining
Healthy
Crypt-villus morphology via nuclear staining
Scalable Data:
All-round Phenotypic Profiling via Multiplex Staining and Sequencing
Phenotypic assays monitor the establishment of cell morphology and phenotype of interest in a target-agnostic manner, enabling the exploration of vast biological space. By leveraging advanced multiplex imaging techniques, we can profile the molecular characteristics of organoids at the single-cell level.
Healthy
Stem cells via LGR5 staining
CRC
Permeability via ZO-1 staining
Healthy
Crypt-villus morphology via nuclear staining
CRC
Crypt-villus morphology via nuclear staining
Healthy
Permeability via ZO-1 staining
CRC
Permeability via ZO-1 staining
Healthy
Stem cells via LGR5 staining
Interested in Partnering or Investing?
Reach out to us through our contact form. We're excited to explore new opportunities together!
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